(WellnessNova.com) - Sucralose, the artificial sweetener marketed as Splenda, may increase the risk of developing leukemia and other types of cancer, according to recent research.
The research, published in a recent issue of the International Journal of Occupational and Environmental Health, studied the effects of the sweetener once classified by the Ramazzini Institute as “safe” before being downgraded to a “caution” warning in 2013.
According to the researchers, a significant cancer risk increase presented in the (mice) subjects as sucralose in the diet increased.
“The researchers also detected a substantially higher incidence of leukemia in the male rodents whose dose levels of sucralose reached 2,000 to 16,000 ppm,” reports TechTimes.
Splenda has been on the market for two decades, marketed as a healthy alternative to other artificial sweeteners as well as white sugar. It’s about 600 times sweeter than sugar and more than three times as sweet as aspartame, the popular yet controversial artificial sweetener in Diet Coke and many other products. But the researchers say sucralose is not an inert ingredient, and should be approached with caution.
“More studies are necessary to show the safety of sucralose, including new and more adequate carcinogenic bioassay on rats,” the study authors wrote.
Heartland Food Products, which manufactures Splenda refuted the research, calling it “unreliable.”
“Extensive research strongly supports that sucralose is safe for everyone and does not cause cancer,” the company’s statement read.